Acetazolamide is a mild … �A~�L>&G. See WARNINGS and PRECAUTIONS. Each 10 mL vial contains Sodium Lactate, anhydrous 5.6 g (50 mEq each of Na+ and lactate anion). The recommended amount to use is about 1 … Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Sodium Lactate. Sodium L-lactate ~98% Synonym: (S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt CAS Number 867-56-1. Safety Data Sheets Download. Significant hypokalemia may occur. KCl is sometimes administered to alkalemic patients. Sodium Lactate Powder. Email: info@alfa-chemistry.com Tel:1-201-478-8534 1-516-662-5404 Fax: 1-516-927-0118 Address: 2200 Smithtown Avenue, Room 1 Ronkonkoma, NY 11779-7329 USA For product inquiries, please use our online system or send an email to inquiry@alfa-chemistry.com It is derived from natural L(+) lactic acid, a weak acid having a dissociation 86 constant of 1.389.10-4 at 22°C (pKa=3.857).Sodium lactate has a content of 59-61% (w/w) and a Molecular weight calculation: 22.98977 + 12.0107*3 + 1.00794*5 + 15.9994*3 Product Information. The solution is administered after dilution by the intravenous route as an electrolyte replenisher and systemic alkalizer. Sodium ions are known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. It is naturally produced in the skin, according to an article published in Cosmetics and Toiletries, and also occurs naturally in all animal and human muscle tissue, according to Sodium-Lactate.com. Demonstrates an anti-drying effect in various foods, particularly delicacies and confectioneries. Simply measure out the sodium lactate, and stir into the cool lye water. See CONTRAINDICATIONS. The sodium salt of lactic acid.It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. It is also not known whether Sodium Lactate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Sodium Lactate and Soap. Sodium Lactate is a sodium salt of racemic or inactive lactic acid with alkalinizing and electrolyte replenishing property. An organic sodium salt having lactate as the counterion. Page 1 of 6 Sodium Lactate 60% Solution CAS No 72-17-3 MATERIAL SAFETY DATA SHEET SDS/MSDS . Sodium lactate hardens cold process soap so you can unmold and enjoy it more quickly. Uses of Sodium Lactate: It is used to treat or prevent acid problems in the blood. It should not be administered undiluted. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The potentially large loads of sodium given with lactate require that caution be exercised in patients with congestive heart failure or other edematous or sodium-retaining states, as well as in patients with oliguria or anuria. �`z�O�ᄐ�/_�G!&���Z::��y np֬�9�Up���5�Ԝ���(e�H�x/.�l}���6���A�G8W4��_���X��s|���o�3�|��f�`@!P1��e�n�{�����6��_��r�/�����)��[�$�r%�1�\�7,�a�8A��*Ha5��!+��v����-X��t��"�6�U�\R��]�m��4L���SPg�A��a� �=7d ��x^�ɰ袯yN�;�p�� ��,� )o�����(��ȑx�y3�4����BϦE�i�46�qp0�>NyX_l|�)�k����.�ح�.�M�z9OS��| �؁x�� ����Lػ��6+�Wq��W�DKY��l Ultralac SL -60 (Sodium Lactate 60%) General Characteristics: Appearance: Clear, colorless liquid. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. 72-17-3. It is seldom measured as such and thus is one of the "unmeasured anions" ("anion gap") in determinations of the ionic composition of plasma. It occurs naturally in the skin as part of the skin’s NMF (Natural Moisturizing Factors), and is an excellent humectant. Sodium Acetate Anhydrous is the anhydrous, sodium salt form of acetic acid.Sodium acetate anhydrous disassociates in water to form sodium ions (Na+) and acetate ions. ... An organic sodium salt having lactate as … Excessive administration of potassium-free solutions may result in significant hypokalemia. MDL number MFCD00066576. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. It is a free flowing hygroscopic salt and has a neutral pH.-Chemical name: Sodium lactate powder-Standard: Food grade FCC-Appearance: crystalline powder-Color: white color-Odor: odorless CHF, shock, respiratory alkalosis or other conditions that increase lactate. Sodium is the principal cation of extracellular fluid. In the liver, lactate is metabolized to glycogen which is ultimately converted to carbon dioxide and water by oxidative metabolism. The lactate in Compound Sodium Lactate solution is metabolized by both oxidation and gluconeogenesis, predominantly in the liver, and bicarbonate is generated by both processes over 1-2 h. When medication is added to Compound Sodium Lactate Solution, the overall pharmacokinetics of the solution will depend on the nature of the drug used. ››Sodium Lactate molecular weight. Molecular Formula C 3 H 5 NaO 3; Average mass 112.060 Da; Monoisotopic mass 112.013641 Da; ChemSpider ID 6049 - Charge. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration. The safety and effectiveness of Sodium Lactate have not been established in pediatric patients. Sodium lactate 1/6 molar in plastic container . When oxidative activity is intact, one to two hours time is required for conversion of lactate to bicarbonate. vitamins, herbal supplements, etc. MF: C3H5O3 Na, MW: 112.1 If you have an allergy to sodium lactate or any other part of sodium lactate. Dosage Form: injection, solution, concentrate. CAUTION: MUST BE DILUTED. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is a sterile, nonpyrogenic, concentrated solution of Sodium Lactate in water for injection. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Sodium Lactate CAS Number 72-17-3 or 867-56-1, EINECS EC Number 200-772-0, HS Code ---**; Molecular Weight 112.06, Molecular Formula: C 3 H 5 NaO 3. Upon metabolism, sodium lactate is converted to bicarbonate, thereby increasing plasma bicarbonate, which facilitates removal of hydrogen ion and lactate … The solution contains no bacteriostat, antimicrobial agent or added buffer. Sodium Lactate, USP is chemically designated CH3CH(OH)COONa, a 60% aqueous solution miscible in water. for the sake); seasoning materials; flavor modifiers; anti-cold agent; quality improver for baked … If you are allergic to sodium lactate; any part of sodium lactate; or any other drugs, foods, or substances. This solution is stable under normal storage conditions. The safety of the plastic has been confirmed by tests in animals according to USP biological standards for plastic containers. When diluted with water for injection to make a 1/6 molar solution, the pH of Sodium Lactate injection is 6.5 (6.0 to 7.3). The normal plasma level of lactate ranges from 0.9 to 1.9 mEq/liter. CAUTION: MUST BE DILUTED. Jungbunzlauer sodium L (+)-lactate is a colourless to yellowish, nearly odourless aqueous solution with a mild salty taste. Adverse effects of Sodium Lactate are essentially limited to overdosage of either sodium or lactate ions. Because many drugs are excreted in human milk, caution should be exercised when Sodium Lactate Injection is administered to a nursing mother. Sodium lactate and NH4Cl should not be administered to patients with liver disease. Its limited use has been inadequate to fully define proper dosage and limitations for use. 80 Sodium Lactate 81 The structural formula for sodium lactate is: 82 83 Figure 2: The structural formula of sodium lactate 84 85 Sodium lactate is hygroscopic. No advantage over sodium bicarbonate and is contraindicated in the treatment of lactic acidosis. Our team of experts are at the ready. In the soap making process, sodium lactate is added to the lye/water solution once the temperature is below 54 degrees Celsius. EC Number 212-762-3. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. per pound of oils. SECTION 4: First aid … Additive Number. Sodium Lactate has no advantage over sodium bicarbonate and may be detrimental in the management of lactic acidosis. ], Distributed by Hospira, INC., Lake Forest, IL 60045 USA. FOR INTRAVENOUS USE. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL) is administered intravenously only after addition to a larger volume of fluid. ).Some health conditions may make you more susceptible to the side-effects of the drug. For Intravenous Use. chemBlink provides information about CAS # 72-17-3, Sodium lactate, Sodium DL-lactate, Lactic acid sodium salt, (+/-)-2-Hydroxypropionic acid sodium salt, molecular formula: C3H5NaO3. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Cautions. Before using Sodium Lactate, inform your doctor about your current list of medications, over the counter products (e.g. Too rapid administration and overdosage should be avoided. It should not be administered undiluted. Sodium Lactate. The amount of sodium ion and lactate ion to be added to larger volume intravenous fluids should be determined in accordance with the electrolyte requirements of each individual patient. It is not known whether this drug is excreted in human milk. It's a liquid salt derived from the fermentation of sugars found in corn and beets. It comprises more than 90% of total cations at its normal plasma concentration of approximately 140 mEq/liter. PROPANOIC ACID, 2-HYDROXY-,MONOSODIUM SALT Propanoic Acid, 2-Hydroxy-, Monosodium Salt. Store at 20 to 25°C (68 to 77°F). It should not be used in conditions in which lactate levels are increased (e.g., shock, congestive heart failure, respiratory alkalosis) or in which utilization of lactate is diminished (e.g., anoxia, beriberi). : 72-17-3 General description: Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). PubChem Substance ID 24896392. Sodium lactate is used in soap making to produce a harder long lasting bar of soap. Stars This entity has been manually annotated by the ChEBI Team. Select one or more newsletters to continue. It is a copolymer of ethylene and propylene. Bacteriostatic effect of Sodium Lactate 50%. Buy Sodium Lactate at BrambleBerry. In the event of overdosage, discontinue infusion containing Sodium Lactate immediately and institute corrective therapy as indicated to reduce elevated serum sodium levels and restore acid-base balance if necessary. Sodium Lactate Injection, USP 50 mEq must be suitably diluted before infusion to avoid a sudden increase in the level of sodium or lactate. China Sodium Lactate manufacturers - Select 2020 high quality Sodium Lactate products in best price from certified Chinese High Pressure Sodium manufacturers, Sodium Phosphate suppliers, wholesalers and factory on Made-in-China.com 325. pregnancy, upcoming surgery, etc. SMILES. It is not intended nor effective for correcting severe acidotic states which require immediate restoration of plasma bicarbonate levels. [See USP Controlled Room Temperature. Since metabolic conversion of lactate to bicarbonate is dependent on the integrity of cellular oxidative processes, lactate may be inadequate or ineffective as a source of bicarbonate in patients suffering from acidosis associated with shock or other disorders involving reduced perfusion of body tissues. Synonym: (S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt, Sodium L-lactate Empirical Formula (Hill Notation): C 3 H 5 NaO 3 Molecular Weight: 112.06 Sodium 2-hydroxyprop anoate. Sodium Lactate injection, solution, concentrate, We comply with the HONcode standard for trustworthy health information -, ANALYSIS(0409-6664), LABEL(0409-6664), MANUFACTURE(0409-6664), PACK(0409-6664). CAS names . Animal reproduction studies have not been conducted with Sodium Lactate. It's a natural ingredient approved by both ECOCERT and COSMOS. Sodium Lactate. Solutions containing sodium ions should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exists edema with sodium retention. Sodium lactate in plastic container . Sodium Lactate Injection, USP 50 mEq is contraindicated in patients suffering from hypernatremia or fluid retention. This solution is stable under normal storage conditions, non-toxic to humans and the environment and readily biodegradable. You can also use it in lotion to draw moisture to the skin, or in hot process soap to make it more fluid and smooth. Jungbunzlauer sodium L (+)-lactate/sodium diacetate is a colourless to yellowish, syrupy liquid with a slight characteristic odour and a saline taste. All or part of the content(s) of one (50 mEq in 10 mL) or more vial containers may be added to other intravenous solutions to provide any desired number of milliequivalents of lactate anion (with the same number of milliequivalents of Na+). What do I need to tell my doctor BEFORE I take Sodium Lactate? Rx only. Below are two batches of … Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is a sterile, nonpyrogenic, concentrated solution of Sodium Lactate in water for injection. Contains hydrochloric acid for pH adjustment. Last updated on Dec 1, 2019. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is primarily indicated, after dilution, as a source of bicarbonate for prevention or control of mild to moderate metabolic acidosis in patients with restricted oral intake whose oxidative processes are not seriously impaired. Specifications of Sodium Lactate Manufacturers. In patients with diminished renal function, administration of solutions containing sodium ions may result in sodium retention. The solution is administered after dilution by the intravenous route as an electrolyte replenisher and systemic alkalizer. The lactate anion is in equilibrium with pyruvate and has an alkalizing effect resulting from simultaneous removal by the liver of lactate and hydrogen ions. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Molar mass of NaC3H5O3 = 112.05977 g/mol Convert grams Sodium Lactate to moles or moles Sodium Lactate to grams. The osmolar concentration is 10 mOsmol/mL (calc.). The sodium ion exerts a primary role in controlling total body water and its distribution. Contains 25 of NDC 0409-6664-11 Formula : C3H5NaO3 Molecular Weight : 112,06 g/mol No components need to be disclosed according to the applicable regulations. by Hospira, Inc., Lake Forest, IL 60045 USA, NDC 0409-6664-02 The intravenous administration of this solution (after appropriate dilution) can cause fluid and/or solute overloading resulting in dilution of other serum electrolyte concentrations, overhydration, congested states or pulmonary edema. You need this product in your collection. Sodium Lactate. Sodium lactate solution is a natural food additive, it is used as water retention agent, antioxidant synergists, emulsifiers, also can be used as pH adjusting agents (e.g. The container requires no vapor barrier to maintain the proper drug concentration. Empirical Formula (Hill Notation) C 3 H 5 NaO 3. Avoid rapid administration and overdosage. It is a significantly stronger humectant than vegetable glycerin, with over twice the water holding capability. Sodium lactate is non-toxic to humans and the environment and is readily biodegradable. ), allergies, pre-existing diseases, and current health conditions (e.g. Solutions containing lactate ions should be used with caution as excess administration may result in metabolic alkalosis. Sodium lactate powder is the solid sodium salt of natural L-Lactic acid, Sodium lactate powder 98 is a white powder. Sodium lactate is the sodium salt of lactic acid. Lactate anion [CH3CH(OH)COO−] serves the important purpose of providing "raw material" for subsequent regeneration of bicarbonate (HCO3−) and thus acts as a source (alternate) of bicarbonate when normal production and utilization of lactic acid is not impaired as a result of disordered lactate metabolism. NOT FOR USE IN THE TREATMENT OF LACTIC ACIDOSIS. Dist. More details: Systematic name. An evaluation of current literature revealed no clinical experience identifying differences in response between elderly and younger patients. Isotonic saline infusion can be used to expand the extracellular fluid volume, and it is also acidifying. Sodium lactate (sodium lactate injection in aviva) is chemically designated as propanoic acid, 2-hydroxy-,monosodium salt and has the following structural formula: CH 3 CH (OH)COONa C 3 H 5 NaO 3 112.1 A 60% aqueous solution is miscible in water. Other Names. Other . Medically reviewed by Drugs.com. The usage rate for sodium lactate is 1 tsp. Discard unused portion. Sodium Lactate is one of the Natural Moisturizing Factor (NMF) constituent of skin, required in the maintenance of natural hydration. Chemical Formula: C3H5NaO3 Molecular Weight: 112.06 CAS#: 867-56-1 (General: 72-17-3) Allergen Status: Product does not contain any of the known allergens including dairy, egg, wheat, soy, tree nuts, peanuts, fish and shellfish. See WARNINGS and PRECAUTIONS. Lactate is one of the main components of Ringer′s lactate… Sodium is the principal cation of the extracellular fluid and plays a large part in fluid and electrolyte replacement therapies. Studies with Sodium Lactate Injection have not been performed to evaluate carcinogenic potential, mutagenic potential or effects on fertility. The contents of one container (50 mEq in 10 mL) added to 290 mL of a nonelectrolyte solution or of sterile water for injection will provide 300 mL of an approximately isotonic (1/6 molar) concentration of Sodium Lactate (1.9%), containing 167 mEq/liter each of Na+ and lactate anion. About Sodium Lactate Enquire Now. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL) is supplied in 10 mL single-dose plastic vials. Sodium Lactate, a 60% concentration in water, and is the sodium salt of natural L(+)-Lactic Acid, produced through the fermentation of sugar, an alpha hydroxy acid that occurs everywhere in nature. 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